About Vexin
Vexin (VXN) is a protein
from Homo sapiens identified by UniProt accession
Q8TAG6, 207 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Vexin |
|---|
| UniProt accession | Q8TAG6 |
|---|
| Gene | VXN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 207 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- blood metabolite measurement · score 0.16
- body mass index · score 0.09
- lean body mass · score 0.08
- body weight · score 0.07
- body height · score 0.07
- PHF-tau measurement · score 0.07
- waist circumference · score 0.06
- adolescent idiopathic scoliosis · score 0.06
- fat body mass · score 0.03
- daytime rest measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TAG6-F1 | alphafold | PREDICTED | 60.24 | — |
Amino-acid sequence (207 residues)
MMHQIYSCSD ENIEVFTTVI PSKVSSPARR RAKSSQHLLT KNVVIESDLY THQPLELLPH RGDRRDPGDR RRFGRLQTAR PPTAHPAKAS ARPVGISEPK TSNLCGNRAY GKSLIPPVPR ISVKTSASAS LEATAMGTEK GAVLMRGSRH LKKMTEEYPA LPQGAEASLP LTGSASCGVP GILRKMWTRH KKKSEYVGAT NSAFEAD
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