About Fin bud initiation factor homolog
Fin bud initiation factor homolog (FIBIN) is a protein
from Homo sapiens identified by UniProt accession
Q8TAL6, 211 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | Fin bud initiation factor homolog |
|---|
| UniProt accession | Q8TAL6 |
|---|
| Gene | FIBIN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 211 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (65)
Diseases linked to this target (Open Targets).
- body height · score 0.50
- sitting height measurement · score 0.27
- neurodegenerative disease · score 0.27
- hip circumference · score 0.12
- vital capacity · score 0.12
- MODY · score 0.07
- hyperproinsulinemia · score 0.05
- heel bone mineral density · score 0.05
- serum metabolite measurement · score 0.04
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TAL6-F1 | alphafold | PREDICTED | 76.44 | — |
Amino-acid sequence (211 residues)
MVFLKFFCMS FFCHLCQGYF DGPLYPEMSN GTLHHYFVPD GDYEENDDPE KCQLLFRVSD HRRCSQGEGS QVGSLLSLTL REEFTVLGRQ VEDAGRVLEG ISKSISYDLD GEESYGKYLR RESHQIGDAY SNSDKSLTEL ESKFKQGQEQ DSRQESRLNE DFLGMLVHTR SLLKETLDIS VGLRDKYELL ALTIRSHGTR LGRLKNDYLK V
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