Ermin (ERMN)

About Ermin

Ermin (ERMN) is a protein from Homo sapiens identified by UniProt accession Q8TAM6, 284 residues long. MolForge cross-references it against 0 known binders and 129 disease associations.

Target properties

Protein name	Ermin
UniProt accession	Q8TAM6
Gene	ERMN
Organism	Homo sapiens
Length	284 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (129)

Diseases linked to this target (Open Targets).

neurofibrillary tangles measurement · score 0.09
bilirubin measurement · score 0.08
glioblastoma multiforme · score 0.07
Charcot-Marie-Tooth disease type 1A · score 0.07
Charcot-Marie-Tooth disease type 1C · score 0.06
autosomal dominant slowed nerve conduction velocity · score 0.05
chronic inflammatory demyelinating polyneuropathy · score 0.05
Autosomal recessive Charcot-Marie-Tooth disease with hoarseness · score 0.05
Charcot-Marie-Tooth disease type 4J · score 0.05
hereditary neuropathy with liability to pressure palsies · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TAM6-F1	alphafold	PREDICTED	57.57	—

Amino-acid sequence (284 residues)

MTDVPATFTQ AECNGDKPPE NGQQTITKIS EELTDVDSPL PHYRVEPSLE GALTKGSQEE RRKLQGNMLL NSSMEDKMLK ENPEEKLFIV HKAITDLSLQ ETSADEMTFR EGHQWEKIPL SGSNQEIRRQ KERITEQPLK EEEDEDRKNK GHQAAEIEWL GFRKPSQADM LHSKHDEEQK VWDEEIDDDD DDNCNNDEDE VRVIEFKKKH EEVSQFKEEG DASEDSPLSS ASSQAVTPDE QPTLGKKSDI SRNAYSRYNT ISYRKIRKGN TKQRIDEFES MMHL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards