LIM domain only protein 3 (LMO3)

About LIM domain only protein 3

LIM domain only protein 3 (LMO3) is a protein from Homo sapiens identified by UniProt accession Q8TAP4, 145 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	LIM domain only protein 3
UniProt accession	Q8TAP4
Gene	LMO3
Organism	Homo sapiens
Length	145 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.42
smoking status measurement · score 0.38
triglyceride measurement · score 0.38
worry measurement · score 0.37
cigarettes per day measurement · score 0.31
mathematical ability · score 0.30
smoking cessation · score 0.30
smoking initiation · score 0.30
body mass index · score 0.29
brain volume measurement · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TAP4-F1	alphafold	PREDICTED	88.31	—

Amino-acid sequence (145 residues)

MLSVQPDTKP KGCAGCNRKI KDRYLLKALD KYWHEDCLKC ACCDCRLGEV GSTLYTKANL ILCRRDYLRL FGVTGNCAAC SKLIPAFEMV MRAKDNVYHL DCFACQLCNQ RFCVGDKFFL KNNMILCQTD YEEGLMKEGY APQVR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards