About Centrosomal protein of 76 kDa
Centrosomal protein of 76 kDa (CEP76) is a protein
from Homo sapiens identified by UniProt accession
Q8TAP6, 659 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Centrosomal protein of 76 kDa |
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| UniProt accession | Q8TAP6 |
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| Gene | CEP76 |
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| Organism | Homo sapiens |
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| Length | 659 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TAP6-F1 | alphafold | PREDICTED | 86.92 | — |
Amino-acid sequence (659 residues)
MSLPPEKASE LKQLIHQQLS KMDVHGRIRE ILAETIREEL APDQQHLSTE DLIKALRRRG IIDDVMKELN FVTDSVEQEL PSSPKQPICF DRQSTLKKTN IDPTRRYLYL QVLGGKAFLE HLQEPEPLPG QVCSTFTLCL HYRNQRFRSK PVPCACEPDF HDGFLLEVHR ESLGDGTRMA DSTTMLSISD PIHMVLIKTD IFGETTLVAS YFLEWRSVLG SENGVTSLTV ELMGVGTESK VSVGILNIKL EMYPPLNQTL SQEVVNTQLA LERQKTAEKE RLFLVYAKQW WREYLQIRPS HNSRLVKIFA QDENGINRPV CSYVKPLRAG RLLDTPRQAA RFVNVLGYER APVIGGGGKQ EQWCTLLAFL CRNKGDCEDH ANLLCSLLLG YGLEAFVCVG TKAKGVPHAW VMTCGTDGAI TFWESLTGHR YIHKPTNPDE PPVAEQPKPL YPYRTIGCVF NHQMFLGNCQ PSDAVETCVF DLNDESKWKP MSEEAIKSVC APGATTSLPP FPPLCASTID ASVTSNEIEM QLRLLVSEHR KDLGLTTVWE DQLSYLLSPA LASYEFERTT SISAGNEEFQ DAIRRAVPDG HTFKGFPIHF VYRNARRAFA TCLRSPFCEE IICCRGDQVR LAVRVRVFTY PESACAVWIM FACKYRSVL
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