M-phase-specific PLK1-interacting protein (MPLKIP)

About M-phase-specific PLK1-interacting protein

M-phase-specific PLK1-interacting protein (MPLKIP) is a protein from Homo sapiens identified by UniProt accession Q8TAP9, 179 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	M-phase-specific PLK1-interacting protein
UniProt accession	Q8TAP9
Gene	MPLKIP
Organism	Homo sapiens
Length	179 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TAP9-F1	alphafold	PREDICTED	56.35	—

Amino-acid sequence (179 residues)

MQRQNFRPPT PPYPGPGGGG WGSGSSFRGT PGGGGPRPPS PRDGYGSPHH TPPYGPRSRP YGSSHSPRHG GSFPGGRFGS PSPGGYPGSY SRSPAGSQQQ FGYSPGQQQT HPQGSPRTST PFGSGRVREK RMSNELENYF KPSMLEDPWA GLEPVSVVDI SQQYSNTQTF TGKKGRYFC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards