Fibroblast growth factor-binding protein 3 (FGFBP3)

About Fibroblast growth factor-binding protein 3

Fibroblast growth factor-binding protein 3 (FGFBP3) is a protein from Homo sapiens identified by UniProt accession Q8TAT2, 258 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	Fibroblast growth factor-binding protein 3
UniProt accession	Q8TAT2
Gene	FGFBP3
Organism	Homo sapiens
Length	258 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (56)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.38
sex hormone-binding globulin measurement · score 0.21
neutrophil count · score 0.19
leukocyte count · score 0.13
alkaline phosphatase measurement · score 0.12
head and neck squamous cell carcinoma · score 0.11
testosterone measurement · score 0.07
myeloid white cell count · score 0.07
appendicular lean mass · score 0.07
major depressive disorder · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TAT2-F1	alphafold	PREDICTED	68.10	—

Amino-acid sequence (258 residues)

MTPPKLRASL SPSLLLLLSG CLLAAARREK GAASNVAEPV PGPTGGSSGR FLSPEQHACS WQLLLPAPEA AAGSELALRC QSPDGARHQC AYRGHPERCA AYAARRAHFW KQVLGGLRKK RRPCHDPAPL QARLCAGKKG HGAELRLVPR ASPPARPTVA GFAGESKPRA RNRGRTRERA SGPAAGTPPP QSAPPKENPS ERKTNEGKRK AALVPNEERP MGTGPDPDGL DGNAELTETY CAEKWHSLCN FFVNFWNG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards