Zinc finger protein 417 (ZNF417)

About Zinc finger protein 417

Zinc finger protein 417 (ZNF417) is a protein from Homo sapiens identified by UniProt accession Q8TAU3, 575 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Zinc finger protein 417
UniProt accession	Q8TAU3
Gene	ZNF417
Organism	Homo sapiens
Length	575 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.23
lymphatic system disease · score 0.21
mean platelet volume · score 0.17
upper respiratory tract disorder · score 0.09
mean corpuscular volume · score 0.04
infect · score 0.02
infection · score 0.02
viral disease · score 0.01
diffuse large B-cell lymphoma · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TAU3-F1	alphafold	PREDICTED	64.35	—

Amino-acid sequence (575 residues)

MAAAAPRRPT QQGTVTFEDV AVNFSQEEWC LLSEAQRCLY RDVMLENLAL ISSLGCWCGS KDEEAPCKQR ISVQRESQSR TPRAGVSPKK AHPCEMCGLI LEDVFHFADH QETHHKQKLN RSGACGKNLD DTAYLHQHQK QHIGEKFYRK SVREASFVKK RKLRVSQEPF VFREFGKDVL PSSGLCQEAA AVEKTDSETM HGPPFQEGKT NYSCGKRTKA FSTKHSVIPH QKLFTRDGCY VCSDCGKSFS RYVSFSNHQR DHTAKGPYDC GECGKSYSRK SSLIQHQRVH TGKTAYPCEE CGKSFSQKGS LISHQRVHTG ERPYECREYG KSFGQKGNLI QHQQGHTGER AYHCGECGKS FRQKFCFINH QRVHTGERPY KCGECGKSFG QKGNLVQHQR GHTGERPYEC KECGKSFRYR SHLTEHQRLH TGERPYNCRE CGKLFNRKYH LLVHERVHTG ERPYACEVCG KLFGNKNCVT IHQRIHTGER PYECNECGKS FLSSSALHVH KRVHSGQKPY KCSECGKSFA ECSSLIKHRR IHTGERPYEC TKCGKTFQRS STLLHHQSSH RRKAL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards