About Protein odd-skipped-related 1
Protein odd-skipped-related 1 (OSR1) is a protein
from Homo sapiens identified by UniProt accession
Q8TAX0, 266 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Protein odd-skipped-related 1 |
| UniProt accession | Q8TAX0 |
| Gene | OSR1 |
| Organism | Homo sapiens |
| Length | 266 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (80)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.32
- body height · score 0.32
- heel bone mineral density · score 0.30
- systolic blood pressure · score 0.30
- vital capacity · score 0.29
- cup-to-disc ratio measurement · score 0.29
- glucose metabolism decline measurement · score 0.28
- breast carcinoma · score 0.27
- sitting height measurement · score 0.27
- cortical surface area measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8TAX0-F1 | alphafold | PREDICTED | 59.58 | — |
Amino-acid sequence (266 residues)
MGSKTLPAPV PIHPSLQLTN YSFLQAVNGL PTVPSDHLPN LYGFSALHAV HLHQWTLGYP AMHLPRSSFS KVPGTVSSLV DARFQLPAFP WFPHVIQPKP EITAGGSVPA LKTKPRFDFA NLALAATQED PAKLGRGEGP GSPAGGLGAL LDVTKLSPEK KPTRGRLPSK TKKEFVCKFC GRHFTKSYNL LIHERTHTDE RPYTCDICHK AFRRQDHLRD HRYIHSKEKP FKCQECGKGF CQSRTLAVHK TLHSQVKELK TSKIKC
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