Mucin-7 (MUC7)

About Mucin-7

Mucin-7 (MUC7) is a protein from Homo sapiens identified by UniProt accession Q8TAX7, 377 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.

Target properties

Protein name	Mucin-7
UniProt accession	Q8TAX7
Gene	MUC7
Organism	Homo sapiens
Length	377 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (107)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.27
squamous cell lung carcinoma · score 0.27
lung adenocarcinoma · score 0.26
breast adenocarcinoma · score 0.26
endometrial cancer · score 0.25
thyroid gland adenocarcinoma · score 0.22
head and neck squamous cell carcinoma · score 0.22
gastric adenocarcinoma · score 0.17
urinary bladder carcinoma · score 0.05
Asthma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TAX7-F1	alphafold	PREDICTED	55.00	—

Amino-acid sequence (377 residues)

MKTLPLFVCI CALSACFSFS EGRERDHELR HRRHHHQSPK SHFELPHYPG LLAHQKPFIR KSYKCLHKRC RPKLPPSPNN PPKFPNPHQP PKHPDKNSSV VNPTLVATTQ IPSVTFPSAS TKITTLPNVT FLPQNATTIS SRENVNTSSS VATLAPVNSP APQDTTAAPP TPSATTPAPP SSSAPPETTA APPTPSATTQ APPSSSAPPE TTAAPPTPPA TTPAPPSSSA PPETTAAPPT PSATTPAPLS SSAPPETTAV PPTPSATTLD PSSASAPPET TAAPPTPSAT TPAPPSSPAP QETTAAPITT PNSSPTTLAP DTSETSAAPT HQTTTSVTTQ TTTTKQPTSA PGQNKISRFL LYMKNLLNRI IDDMVEQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards