About Spermatogenesis-associated protein 20
Spermatogenesis-associated protein 20 (SPATA20) is a protein
from Homo sapiens identified by UniProt accession
Q8TB22, 786 residues long.
MolForge cross-references it against 0 known binders and
138 disease associations.
Target properties
| Protein name | Spermatogenesis-associated protein 20 |
|---|
| UniProt accession | Q8TB22 |
|---|
| Gene | SPATA20 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 786 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (138)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.35
- creatinine measurement · score 0.32
- triglyceride measurement · score 0.32
- blood protein measurement · score 0.31
- sex hormone-binding globulin measurement · score 0.28
- heel bone mineral density · score 0.27
- serum gamma-glutamyl transferase measurement · score 0.26
- glomerular filtration rate · score 0.26
- BMI-adjusted hip circumference · score 0.24
- reticulocyte measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TB22-F1 | alphafold | PREDICTED | 89.72 | — |
Amino-acid sequence (786 residues)
MLGARAWLGR VLLLPRAGAG LAASRRGSSS RDKDRSATVS SSVPMPAGGK GSHPSSTPQR VPNRLIHEKS PYLLQHAYNP VDWYPWGQEA FDKARKENKP IFLSVGYSTC HWCHMMEEES FQNEEIGRLL SEDFVSVKVD REERPDVDKV YMTFVQATSS GGGWPMNVWL TPNLQPFVGG TYFPPEDGLT RVGFRTVLLR IREQWKQNKN TLLENSQRVT TALLARSEIS VGDRQLPPSA ATVNNRCFQQ LDEGYDEEYG GFAEAPKFPT PVILSFLFSY WLSHRLTQDG SRAQQMALHT LKMMANGGIR DHVGQGFHRY STDRQWHVPH FEKMLYDQAQ LAVAYSQAFQ LSGDEFYSDV AKGILQYVAR SLSHRSGGFY SAEDADSPPE RGQRPKEGAY YVWTVKEVQQ LLPEPVLGAT EPLTSGQLLM KHYGLTEAGN ISPSQDPKGE LQGQNVLTVR YSLELTAARF GLDVEAVRTL LNSGLEKLFQ ARKHRPKPHL DSKMLAAWNG LMVSGYAVTG AVLGQDRLIN YATNGAKFLK RHMFDVASGR LMRTCYTGPG GTVEHSNPPC WGFLEDYAFV VRGLLDLYEA SQESAWLEWA LRLQDTQDKL FWDSQGGGYF CSEAELGAGL PLRLKDDQDG AEPSANSVSA HNLLRLHGFT GHKDWMDKCV CLLTAFSERM RRVPVALPEM VRALSAQQQT LKQIVICGDR QAKDTKALVQ CVHSVYIPNK VLILADGDPS SFLSRQLPFL STLRRLEDQA TAYVCENQAC SVPITDPCEL RKLLHP
Explore Spermatogenesis-associated protein 20 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets