Protein NDNF (NDNF)

About Protein NDNF

Protein NDNF (NDNF) is a protein from Homo sapiens identified by UniProt accession Q8TB73, 568 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.

Target properties

Protein name	Protein NDNF
UniProt accession	Q8TB73
Gene	NDNF
Organism	Homo sapiens
Length	568 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (105)

Diseases linked to this target (Open Targets).

Kallmann syndrome · score 0.61
neurodegenerative disease · score 0.37
facial morphology measurement · score 0.29
lip morphology measurement · score 0.29
protein measurement · score 0.05
multiple sclerosis · score 0.05
Miyoshi myopathy · score 0.05
sitting height measurement · score 0.05
spinal muscular atrophy, facioscapulohumeral type · score 0.04
myocardial infarction · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TB73-F1	alphafold	PREDICTED	78.62	—

Amino-acid sequence (568 residues)

MVLLHWCLLW LLFPLSSRTQ KLPTRDEELF QMQIRDKAFF HDSSVIPDGA EISSYLFRDT PKRYFFVVEE DNTPLSVTVT PCDAPLEWKL SLQELPEDRS GEGSGDLEPL EQQKQQIINE EGTELFSYKG NDVEYFISSS SPSGLYQLDL LSTEKDTHFK VYATTTPESD QPYPELPYDP RVDVTSLGRT TVTLAWKPSP TASLLKQPIQ YCVVINKEHN FKSLCAVEAK LSADDAFMMA PKPGLDFSPF DFAHFGFPSD NSGKERSFQA KPSPKLGRHV YSRPKVDIQK ICIGNKNIFT VSDLKPDTQY YFDVFVVNIN SNMSTAYVGT FARTKEEAKQ KTVELKDGKI TDVFVKRKGA KFLRFAPVSS HQKVTFFIHS CLDAVQIQVR RDGKLLLSQN VEGIQQFQLR GKPKAKYLVR LKGNKKGASM LKILATTRPT KQSFPSLPED TRIKAFDKLR TCSSATVAWL GTQERNKFCI YKKEVDDNYN EDQKKREQNQ CLGPDIRKKS EKVLCKYFHS QNLQKAVTTE TIKGLQPGKS YLLDVYVIGH GGHSVKYQSK VVKTRKFC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards