About Golgin subfamily A member 5
Golgin subfamily A member 5 (GOLGA5) is a protein
from Homo sapiens identified by UniProt accession
Q8TBA6, 731 residues long.
MolForge cross-references it against 0 known binders and
137 disease associations.
Target properties
| Protein name | Golgin subfamily A member 5 |
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| UniProt accession | Q8TBA6 |
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| Gene | GOLGA5 |
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| Organism | Homo sapiens |
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| Length | 731 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (137)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- spitz nevus · score 0.37
- papillary thyroid carcinoma · score 0.37
- Thyroid Gland Oncocytic Follicular Carcinoma · score 0.37
- thyroid gland oncocytic adenoma · score 0.37
- melanocytic neoplasm · score 0.37
- Benign Thyroid Gland Neoplasm · score 0.37
- Follicular Variant Thyroid Gland Papillary Carcinoma · score 0.37
- Poorly Differentiated Thyroid Gland Carcinoma · score 0.28
- gastric carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TBA6-F1 | alphafold | PREDICTED | 71.56 | — |
Amino-acid sequence (731 residues)
MSWFVDLAGK AEDLLNRVDQ GAATALSRKD NASNIYSKNT DYTELHQQNT DLIYQTGPKS TYISSAADNI RNQKATILAG TANVKVGSRT PVEASHPVEN ASVPRPSSHF VRRKKSEPDD ELLFDFLNSS QKEPTGRVEI RKEKGKTPVF QSSQTSSVSS VNPSVTTIKT IEENSFGSQT HEAASNSDSS HEGQEESSKE NVSSNAACPD HTPTPNDDGK SHELSNLRLE NQLLRNEVQS LNQEMASLLQ RSKETQEELN KARARVEKWN ADHSKSDRMT RGLRAQVDDL TEAVAAKDSQ LAVLKVRLQE ADQLLSTRTE ALEALQSEKS RIMQDQSEGN SLQNQALQTF QERLHEADAT LKREQESYKQ MQSEFAARLN KVEMERQNLA EAITLAERKY SDEKKRVDEL QQQVKLYKLN LESSKQELID YKQKATRILQ SKEKLINSLK EGSGFEGLDS STASSMELEE LRHEKEMQRE EIQKLMGQIH QLRSELQDME AQQVNEAESA REQLQDLHDQ IAGQKASKQE LETELERLKQ EFHYIEEDLY RTKNTLQSRI KDRDEEIQKL RNQLTNKTLS NSSQSELENR LHQLTETLIQ KQTMLESLST EKNSLVFQLE RLEQQMNSAS GSSSNGSSIN MSGIDNGEGT RLRNVPVLFN DTETNLAGMY GKVRKAASSI DQFSIRLGIF LRRYPIARVF VIIYMALLHL WVMIVLLTYT PEMHHDQPYG K
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