About Bromo adjacent homology domain-containing 1 protein
Bromo adjacent homology domain-containing 1 protein (BAHD1) is a protein
from Homo sapiens identified by UniProt accession
Q8TBE0, 780 residues long.
MolForge cross-references it against 0 known binders and
92 disease associations.
Target properties
| Protein name | Bromo adjacent homology domain-containing 1 protein |
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| UniProt accession | Q8TBE0 |
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| Gene | BAHD1 |
|---|
| Organism | Homo sapiens |
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| Length | 780 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (92)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.20
- high density lipoprotein cholesterol measurement · score 0.18
- immunodeficiency 28 · score 0.06
- Immunodeficiency due to a late component of complements deficiency · score 0.06
- recurrent Neisseria infections due to factor D deficiency · score 0.06
- immunodeficiency 35 · score 0.05
- Immunodeficiency due to interleukin-1 receptor-associated kinase-4 deficiency · score 0.05
- immunodeficiency 31B · score 0.04
- testosterone measurement · score 0.04
- Alymphoid cystic thymic dysgenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TBE0-F1 | alphafold | PREDICTED | 50.37 | — |
Amino-acid sequence (780 residues)
MTHTRRKSLP MLSSGLTGRR EPLQMEDSNM EQGVEGVEPG MPESPGHLTG RRKNYPLRKR PLVPEKPKAC KVLLTRLENV AGPRSADEAD ELPPDLPKPP SPAPSSEDPG LAQPRKRRLA SLNAEALNNL LLEREDTSSL AGTRRSRAGD PHRSRDRDRA TGGWSSSKKR PRLGDLGGGS RDLSPEPAPD EGPRRDGDPA PKRLASLNAA AFLKLSQERE LPLRLPRAHA EVDGRSTEPP APKAPRPKWP KVNGKNYPKA WQGASSGEAA GPPGWQGCPD EPWPSATPCG PSVQPSHQPL SKALESPLGL RPHLPLLMGG QAALKPEPGR PGEESPAPKQ ELHQPSFPTP QLSPLPMPGN PADYNGLCVG PELTALGSFY LYCGQEGLQC GGYSPCPMLP EGKLSPVAAP HEEGLLLAPS SVPSGTPFQH PPWGSSRYCS SEDTGVNGYS ICGVLPLSVT HAGTTCGGCP YKMPFAAEGC RSLGQLEFPL PEAGHPASPA HPLLGCPVPS VPPAAEPVPH LQTPTSEPQT VARACPQSAK PPSGSKSGLR TGSSCRHTAR SKAARRPSHP KQPRVQRPRP RRRRRRRTNG WVPVGAACEK AVYVLDEPEP AIRKSYQAVE RHGETIRVRD TVLLKSGPRK TSTPYVAKIS ALWENPESGE LMMSLLWYYR PEHLQGGRSP SMHEPLQNEV FASRHQDQNS VACIEEKCYV LTFAEYCRFC AMAKRRGEGL PSRKTALVPP SADYSTPPHR TVPEDTDPEL VFLCRHVYDF RHGRILKNPQ
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