Solute carrier family 35 member G2 (SLC35G2)

About Solute carrier family 35 member G2

Solute carrier family 35 member G2 (SLC35G2) is a protein from Homo sapiens identified by UniProt accession Q8TBE7, 412 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.

Target properties

Protein name	Solute carrier family 35 member G2
UniProt accession	Q8TBE7
Gene	SLC35G2
Organism	Homo sapiens
Length	412 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (99)

Diseases linked to this target (Open Targets).

platelet count · score 0.33
lymphocyte count · score 0.31
monocyte count · score 0.30
platelet crit · score 0.29
leukocyte count · score 0.29
waist-hip ratio · score 0.24
serum albumin measurement · score 0.22
central corneal thickness · score 0.22
body height · score 0.21
Red cell distribution width · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TBE7-F1	alphafold	PREDICTED	78.02	—

Amino-acid sequence (412 residues)

MDTSPSRKYP VKKRVKIHPN TVMVKYTSHY PQPGDDGYEE INEGYGNFME ENPKKGLLSE MKKKGRAFFG TMDTLPPPTE DPMINEIGQF QSFAEKNIFQ SRKMWIVLFG SALAHGCVAL ITRLVSDRSK VPSLELIFIR SVFQVLSVLV VCYYQEAPFG PSGYRLRLFF YGVCNVISIT CAYTSFSIVP PSNGTTMWRA TTTVFSAILA FLLVDEKMAY VDMATVVCSI LGVCLVMIPN IVDEDNSLLN AWKEAFGYTM TVMAGLTTAL SMIVYRSIKE KISMWTALFT FGWTGTIWGI STMFILQEPI IPLDGETWSY LIAICVCSTA AFLGVYYALD KFHPALVSTV QHLEIVVAMV LQLLVLHIFP SIYDVFGGVI IMISVFVLAG YKLYWRNLRK QDYQEILDSP IK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards