About TLC domain-containing protein 3A
TLC domain-containing protein 3A (TLCD3A) is a protein
from Homo sapiens identified by UniProt accession
Q8TBR7, 257 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | TLC domain-containing protein 3A |
|---|
| UniProt accession | Q8TBR7 |
|---|
| Gene | TLCD3A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 257 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.14
- Fraser syndrome · score 0.11
- hepatocellular carcinoma · score 0.07
- high density lipoprotein cholesterol measurement · score 0.07
- BMI-adjusted waist circumference · score 0.07
- hip circumference · score 0.06
- physical activity measurement · score 0.06
- eosinophil count · score 0.06
- type 2 diabetes mellitus · score 0.06
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TBR7-F1 | alphafold | PREDICTED | 92.96 | — |
Amino-acid sequence (257 residues)
MLLTLAGGAL FFPGLFALCT WALRRSQPGW SRTDCVMIST RLVSSVHAVL ATGSGIVIIR SCDDVITGRH WLAREYVWFL IPYMIYDSYA MYLCEWCRTR DQNRAPSLTL RNFLSRNRLM ITHHAVILFV LVPVAQRLRG DLGDFFVGCI FTAELSTPFV SLGRVLIQLK QQHTLLYKVN GILTLATFLS CRILLFPFMY WSYGRQQGLS LLQVPFSIPF YCNVANAFLV APQIYWFCLL CRKAVRLFDT PQAKKDG
Explore TLC domain-containing protein 3A with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets