About MYCBP-associated protein
MYCBP-associated protein (MYCBPAP) is a protein
from Homo sapiens identified by UniProt accession
Q8TBZ2, 984 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | MYCBP-associated protein |
|---|
| UniProt accession | Q8TBZ2 |
|---|
| Gene | MYCBPAP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 984 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (3)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.03
- squamous cell carcinoma · score 0.01
- myelodysplastic syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TBZ2-F1 | alphafold | PREDICTED | 59.73 | — |
Amino-acid sequence (984 residues)
MRAPARGTGC CGRSGGRWLA GAAQPRCLWA GGAGQRFMVP GGTMKSLKKD SRLRITPTRL LEASENVKEK KRAKGPEQPT PTIQEEPEPV SNVLQGDDIL ALAIKKEDLK EQHIPRLTEK EDKRVITQKF IIRKLKPMDP RRKVCHLVAR PANPDEATKP LDYSGPGDSF DGSDQILPHH ILGSLQDFKR IALARGNTQL AERIPTSPCL MTLISAEGES KQKAPKEEKR PPWAPPPQHN FLKNWQRNTA LRKKQQEALS EHLKKPVSEL LMHTGETYRR IQEERELIDC TLPTRRDRKS WENSGFWSRL EYLGDEMTGL VMTKTKTQRG LMEPITHIRK PHSIRVETGL PAQRDASYRY TWDRSLFLIY RRKELQRIME ELDFSQQDID GLEVVGKGWP FSAVTVEDYT VFERSQGSSS EDTAYLGTLA SSSDVSMPIL GPSLLFCGKP ACWIRGSNPQ DKRQVGIAAH LTFETLEGEK TSSELTVVNN GTVAIWYDWR RQHQPDTFQD LKKNRMQRFY FDNREGVILP GEIKTFTFFF KSLTAGVFRE FWEFRTHPTL LGGAILQVNL HAVSLTQDVF EDERKVLESK LTAHEAVTVV REVLQELLMG VLTPERTPSP VDAYLTEEDL FRHRNPPLHY EHQVVQSLHQ LWRQYMTLPA KAEEARPGDK EHVSPIATEK ASVNAELLPR FRSPISETQV PRPENEALRE SGSQKARVGT KSPQRKSIME EILVEESPDV DSTKSPWEPD GLPLLEWNLC LEDFRKAVMV LPDENHREDA LMRLNKAALE LCQKPRPLQS NLLHQMCLQL WRDVIDSLVG HSMWLRSVLG LPEKETIYLN VPEEQDQKSP PIMEVKVPVG KAGKEERKGA AQEKKQLGIK DKEDKKGAKL LGKEDRPNSK KHKAKDDKKV IKSASQDRFS LEDPTPDIIL SSQEPIDPLV MGKYTQSLHS EVRGLLDTLV TDLMVLADEL SPIKNVEEAL RLCR
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