Zinc finger protein 596 (ZNF596)

About Zinc finger protein 596

Zinc finger protein 596 (ZNF596) is a protein from Homo sapiens identified by UniProt accession Q8TC21, 504 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Zinc finger protein 596
UniProt accession	Q8TC21
Gene	ZNF596
Organism	Homo sapiens
Length	504 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

breast carcinoma · score 0.35
Kallmann syndrome · score 0.33
hypogonadotropic hypogonadism 5 with or without anosmia · score 0.33
estrogen-receptor negative breast cancer · score 0.28
systolic blood pressure · score 0.28
protein measurement · score 0.13
hematocrit · score 0.08
neoplasm · score 0.02
Ataxia-telangiectasia · score 0.01
glioblastoma multiforme · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TC21-F1	alphafold	PREDICTED	70.33	—

Amino-acid sequence (504 residues)

MPSPDSMTFE DIIVDFTQEE WALLDTSQRK LFQDVMLENI SHLVSIGKQL CKSVVLSQLE QVEKLSTQRI SLLQGREVGI KHQEIPFIQH IYQKGTSTIS TMRSHTQEDP FLCNDLGEDF TQHIALTQNV ITYMRTKHFV SKKFGKIFSD WLSFNQHKEI HTKCKSYGSH LFDYAFIQNS ALRPHSVTHT REITLECRVC GKTFSKNSNL RRHEMIHTGE KPHGCHLCGK AFTHCSDLRK HERTHTGEKP YGCHLCGKAF SKSSNLRRHE MIHTREKAQI CHLCGKAFTH CSDLRKHERT HLGDKPYGCL LCGKAFSKCS YLRQHERTHN GEKPYECHLC GKAFSHCSHL RQHERSHNGE KPHGCHLCGK AFTESSVLKR HERIHTGEKP YECHVCGKAF TESSDLRRHE RTHTGEKPYE CHLCGKAFNH SSVLRRHERT HTGEKPYECN ICGKAFNRSY NFRLHRRVHT GEKPYVCPLC GKAFSKFFNL RQHERTHTKK AMNM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards