About Transmembrane protein 163
Transmembrane protein 163 (TMEM163) is a protein
from Homo sapiens identified by UniProt accession
Q8TC26, 289 residues long.
MolForge cross-references it against 0 known binders and
129 disease associations.
Target properties
| Protein name | Transmembrane protein 163 |
|---|
| UniProt accession | Q8TC26 |
|---|
| Gene | TMEM163 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 289 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (129)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.45
- hair color · score 0.44
- Parkinson disease · score 0.43
- primary biliary cirrhosis · score 0.42
- mathematical ability · score 0.42
- hematocrit · score 0.38
- erythrocyte count · score 0.31
- cutaneous melanoma · score 0.31
- hair colour measurement · score 0.31
- platelet component distribution width · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TC26-F1 | alphafold | PREDICTED | 76.48 | — |
Amino-acid sequence (289 residues)
MEPAAGIQRR SSQGPTVPPP PRGHAPPAAA PGPAPLSSPV REPPQLEEER QVRISESGQF SDGLEDRGLL ESSTRLKPHE AQNYRKKALW VSWFSIIVTL ALAVAAFTVS VMRYSASAFG FAFDAILDVL SSAIVLWRYS NAAAVHSAHR EYIACVILGV IFLLSSICIV VKAIHDLSTR LLPEVDDFLF SVSILSGILC SILAVLKFML GKVLTSRALI TDGFNSLVGG VMGFSILLSA EVFKHDSAVW YLDGSIGVLI GLTIFAYGVK LLIDMVPRVR QTRHYEMFE
Explore Transmembrane protein 163 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets