Protein FAM110B (FAM110B)

About Protein FAM110B

Protein FAM110B (FAM110B) is a protein from Homo sapiens identified by UniProt accession Q8TC76, 370 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Protein FAM110B
UniProt accession	Q8TC76
Gene	FAM110B
Organism	Homo sapiens
Length	370 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.27
metabolite measurement · score 0.26
delta-5 desaturase measurement · score 0.26
response to polyunsaturated fatty acid supplementation · score 0.26
refractive error measurement · score 0.20
brain measurement · score 0.19
emotional symptom measurement · score 0.18
non-small cell lung carcinoma · score 0.07
primary familial polycythemia due to EPO receptor mutation · score 0.05
hemolytic anemia due to diphosphoglycerate mutase deficiency · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TC76-F1	alphafold	PREDICTED	58.64	—

Amino-acid sequence (370 residues)

MPTETLQTGS MVKPVSPAGT FTSAVPLRIL NKGPDYFRRQ AEPNPKRLSA VERLEADKAK YVKSQEVINA KQEPVKPAVL AKPPVCPAAK RALGSPTLKV FGNHAKTESG VQRENLKLEI LKNIINSSEG SSSGSGHKHS SRNWPPHRSE ATDLHRHSFA ESLKVYPTQG RRSPQEGGSH VGRRLLEQSA ESFLHVSHSS SDIRKVTSVK PLKAIPCSSS APPLPPKPKI AAIASMKSPE ADPVEPACGV SRRPSLQRSK SDLSDRYFRV DADVERFFNY CGLDPEELEN LGMENFARAN SDIISLNFRS ASMISSDCEQ SQDSNSDLRN DDSANDRVPY GISAIERNAR IIKWLYSIKQ ARESQKVSHV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards