About Coiled-coil domain-containing glutamate-rich protein 1
Coiled-coil domain-containing glutamate-rich protein 1 (CCER1) is a protein
from Homo sapiens identified by UniProt accession
Q8TC90, 406 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing glutamate-rich protein 1 |
|---|
| UniProt accession | Q8TC90 |
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| Gene | CCER1 |
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| Organism | Homo sapiens |
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| Length | 406 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (24)
Diseases linked to this target (Open Targets).
- body mass index · score 0.31
- puberty onset measurement · score 0.31
- hematocrit · score 0.30
- hemoglobin measurement · score 0.29
- age at first facial hair · score 0.29
- erythrocyte count · score 0.28
- urate measurement · score 0.28
- bone density · score 0.28
- red blood cell density measurement · score 0.24
- appendicular lean mass · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TC90-F1 | alphafold | PREDICTED | 50.12 | — |
Amino-acid sequence (406 residues)
MTQTLDTRED PLNLGGGGGG GCGCGWAHSA SLSSWSSCHR RRPGAPAYNR PHRYSPKTEY GPPRKQPKQQ HGPGFWFQPP VCSNWGCWGG PWRPPPPGFW KFPCPVQVFR VYGLHPLCFC CCSCWSGSWN PGWVKPPGRK KRWGRRGRGL RHHPRHSYPR SPPADVSTLP RPVKLYEWRE PGMRAPPNTT QFIMNQIYED MRQQEKVERQ QEALRAQKAT VSGEASPARS SGNDAPPGGS KETWGLQETL YGFVQNPSLA FSPNPEENQS LAPLLVEEEE EKKNDDEEEY DQEVCDAKEA SEEEEEVEDE EEEVEDEEEE EVEEAEYVEE GEEELEEEEL EEEEEVLEEN EQRGEEFHLP LEMPLSIFVE AEEKRENFIS CTFLNPEQII PKVPQESLFM AQDFNC
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