About Olfactory receptor 51E1
Olfactory receptor 51E1 (OR51E1) is a protein
from Homo sapiens identified by UniProt accession
Q8TCB6, 318 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Olfactory receptor 51E1 |
|---|
| UniProt accession | Q8TCB6 |
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| Gene | OR51E1 |
|---|
| Organism | Homo sapiens |
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| Length | 318 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.31
- clear cell renal carcinoma · score 0.19
- low grade glioma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- smoking behavior · score 0.12
- Barrett's esophagus · score 0.06
- body height · score 0.05
- Moyamoya disease · score 0.04
- non-small cell lung carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCB6-F1 | alphafold | PREDICTED | 88.51 | — |
Amino-acid sequence (318 residues)
MMVDPNGNES SATYFILIGL PGLEEAQFWL AFPLCSLYLI AVLGNLTIIY IVRTEHSLHE PMYIFLCMLS GIDILISTSS MPKMLAIFWF NSTTIQFDAC LLQMFAIHSL SGMESTVLLA MAFDRYVAIC HPLRHATVLT LPRVTKIGVA AVVRGAALMA PLPVFIKQLP FCRSNILSHS YCLHQDVMKL ACDDIRVNVV YGLIVIISAI GLDSLLISFS YLLILKTVLG LTREAQAKAF GTCVSHVCAV FIFYVPFIGL SMVHRFSKRR DSPLPVILAN IYLLVPPVLN PIVYGVKTKE IRQRILRLFH VATHASEP
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