Large ribosomal subunit protein uL30m (MRPL30)

About Large ribosomal subunit protein uL30m

Large ribosomal subunit protein uL30m (MRPL30) is a protein from Homo sapiens identified by UniProt accession Q8TCC3, 161 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL30m
UniProt accession	Q8TCC3
Gene	MRPL30
Organism	Homo sapiens
Length	161 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.52
FEV/FVC ratio · score 0.27
hereditary motor and sensory neuropathy · score 0.06
type 2 diabetes mellitus · score 0.01
Obesity · score 0.00
neoplasm · score 0.00
glioblastoma multiforme · score 0.00
Miyoshi myopathy · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TCC3-F1	alphafold	PREDICTED	82.72	—

Amino-acid sequence (161 residues)

MAGILRLVVQ WPPGRLQTVT KGVESLICTD WIRHKFTRSR IPEKVFQASP EDHEKYGGDP QNPHKLHIVT RIKSTRRRPY WEKDIIKMLG LEKAHTPQVH KNIPSVNAKL KVVKHLIRIK PLKLPQGLPA EENMSNTCLK STGELVVQWH LKPVEQKAHE S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards