About Pyridoxal phosphate phosphatase PHOSPHO2
Pyridoxal phosphate phosphatase PHOSPHO2 (PHOSPHO2) is a protein
from Homo sapiens identified by UniProt accession
Q8TCD6, 241 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Pyridoxal phosphate phosphatase PHOSPHO2 |
|---|
| UniProt accession | Q8TCD6 |
|---|
| Gene | PHOSPHO2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 241 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.39
- monocyte count · score 0.12
- platelet crit · score 0.10
- systolic blood pressure · score 0.08
- body height · score 0.08
- platelet count · score 0.07
- appendicular lean mass · score 0.07
- lymphocyte count · score 0.06
- hepatocellular carcinoma · score 0.02
- serum alanine aminotransferase measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCD6-F1 | alphafold | PREDICTED | 96.06 | — |
Amino-acid sequence (241 residues)
MKILLVFDFD NTIIDDNSDT WIVQCAPNKK LPIELRDSYR KGFWTEFMGR VFKYLGDKGV REHEMKRAVT SLPFTPGMVE LFNFIRKNKD KFDCIIISDS NSVFIDWVLE AASFHDIFDK VFTNPAAFNS NGHLTVENYH THSCNRCPKN LCKKVVLIEF VDKQLQQGVN YTQIVYIGDG GNDVCPVTFL KNDDVAMPRK GYTLQKTLSR MSQNLEPMEY SVVVWSSGVD IISHLQFLIK D
Explore Pyridoxal phosphate phosphatase PHOSPHO2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets