About Placental protein 13-like
Placental protein 13-like (LGALS14) is a protein
from Homo sapiens identified by UniProt accession
Q8TCE9, 139 residues long.
MolForge cross-references it against 0 known binders and
137 disease associations.
Target properties
| Protein name | Placental protein 13-like |
|---|
| UniProt accession | Q8TCE9 |
|---|
| Gene | LGALS14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 139 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (137)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.24
- sum of eosinophil and basophil counts · score 0.10
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.07
- neutrophil percentage of granulocytes · score 0.07
- Familial hemophagocytic lymphohistiocytosis · score 0.05
- Felty's syndrome · score 0.05
- immunodeficiency 72 with autoinflammation · score 0.05
- hyper-IgM syndrome type 3 · score 0.05
- osteoarthritis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCE9-F1 | alphafold | PREDICTED | 97.16 | — |
Amino-acid sequence (139 residues)
MSSLPVPYTL PVSLPVGSCV IITGTPILTF VKDPQLEVNF YTGMDEDSDI AFQFRLHFGH PAIMNSCVFG IWRYEEKCYY LPFEDGKPFE LCIYVRHKEY KVMVNGQRIY NFAHRFPPAS VKMLQVFRDI SLTRVLISD
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