About AN1-type zinc finger protein 1
AN1-type zinc finger protein 1 (ZFAND1) is a protein
from Homo sapiens identified by UniProt accession
Q8TCF1, 268 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | AN1-type zinc finger protein 1 |
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| UniProt accession | Q8TCF1 |
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| Gene | ZFAND1 |
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| Organism | Homo sapiens |
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| Length | 268 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- ovarian carcinoma · score 0.09
- ovarian serous carcinoma · score 0.07
- cystatin C measurement · score 0.06
- malignant epithelial tumor of ovary · score 0.06
- age-related hearing impairment · score 0.06
- mean platelet volume · score 0.05
- blood phosphate measurement · score 0.05
- platelet crit · score 0.05
- platelet count · score 0.04
- reticulocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCF1-F1 | alphafold | PREDICTED | 83.13 | — |
Amino-acid sequence (268 residues)
MAELDIGQHC QVEHCRQRDF LPFVCDDCSG IFCLEHRSRE SHGCPEVTVI NERLKTDQHT SYPCSFKDCA ERELVAVICP YCEKNFCLRH RHQSDHECEK LEIPKPRMAA TQKLVKDIID SKTGETASKR WKGAKNSETA AKVALMKLKM HADGDKSLPQ TERIYFQVFL PKGSKEKSKP MFFCHRWSIG KAIDFAASLA RLKNDNNKFT AKKLRLCHIT SGEALPLDHT LETWIAKEDC PLYNGGNIIL EYLNDEEQFC KNVESYLE
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