About Ciliary microtubule-associated protein 3
Ciliary microtubule-associated protein 3 (CIMAP3) is a protein
from Homo sapiens identified by UniProt accession
Q8TCI5, 191 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Ciliary microtubule-associated protein 3 |
|---|
| UniProt accession | Q8TCI5 |
|---|
| Gene | CIMAP3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 191 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.16
- pancreatic adenocarcinoma · score 0.04
- breast carcinoma · score 0.04
- ependymoma · score 0.03
- atrial fibrillation · score 0.01
- nasopharyngeal neoplasm · score 0.01
- squamous cell carcinoma · score 0.01
- colorectal adenocarcinoma · score 0.01
- endometrial carcinoma · score 0.01
- chronic interstitial cystitis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCI5-F1 | alphafold | PREDICTED | 72.65 | — |
Amino-acid sequence (191 residues)
MCFSRADAAD NYPFGTCQQR KLFPHFHPPN LIGNKFVPLR GSPHRGPGCY FSDGYGLAYD LSKIPTSIKG YTLGARTAVR FKPIQKEMTP HAGRYQKVSP QQEKHKQNFA PFNVLVPRFK NYPKDTYYPS PGAYNPEKKP PPKIAWPMKF GSPDWAQVPC LQKRTLKAEL STDKDFRKHR NRVAYLSLYY N
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