About Zinc finger protein 507
Zinc finger protein 507 (ZNF507) is a protein
from Homo sapiens identified by UniProt accession
Q8TCN5, 953 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Zinc finger protein 507 |
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| UniProt accession | Q8TCN5 |
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| Gene | ZNF507 |
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| Organism | Homo sapiens |
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| Length | 953 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (43)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- body height · score 0.43
- self reported educational attainment · score 0.33
- brain measurement · score 0.30
- nasopharyngeal neoplasm · score 0.29
- coronary artery disease · score 0.28
- PHF-tau measurement · score 0.28
- age at first sexual intercourse measurement · score 0.26
- smoking status measurement · score 0.24
- body mass index · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCN5-F1 | alphafold | PREDICTED | 50.99 | — |
Amino-acid sequence (953 residues)
MEESSSVAML VPDIGEQEAI LTAESIISPS LEIDEQRKTK PDPLIHVIQK LSKIVENEKS QKCLLIGKKR PRSSAATHSL ETQELCEIPA KVIQSPAADT RRAEMSQTNF TPDTLAQNEG KAMSYQCSLC KFLSSSFSVL KDHIKQHGQQ NEVILMCSEC HITSRSQEEL EAHVVNDHDN DANIHTQSKA QQCVSPSSSL CRKTTERNET IPDIPVSVDN LQTHTVQTAS VAEMGRRKWY AYEQYGMYRC LFCSYTCGQQ RMLKTHAWKH AGEVDCSYPI FENENEPLGL LDSSAAAAPG GVDAVVIAIG ESELSIHNGP SVQVQICSSE QLSSSSPLEQ SAERGVHLSQ SVTLDPNEEE MLEVISDAEE NLIPDSLLTS AQKIISSSPN KKGHVNVIVE RLPSAEETLS QKRFLMNTEM EEGKDLSLTE AQIGREGMDD VYRADKCTVD IGGLIIGWSS SEKKDELMNK GLATDENAPP GRRRTNSESL RLHSLAAEAL VTMPIRAAEL TRANLGHYGD INLLDPDTSQ RQVDSTLAAY SKMMSPLKNS SDGLTSLNQS NSTLVALPEG RQELSDGQVK TGISMSLLTV IEKLRERTDQ NASDDDILKE LQDNAQCQPN SDTSLSGNNV VEYIPNAERP YRCRLCHYTS GNKGYIKQHL RVHRQRQPYQ CPICEHIADN SKDLESHMIH HCKTRIYQCK QCEESFHYKS QLRNHEREQH SLPDTLSIAT SNEPRISSDT ADGKCVQEGN KSSVQKQYRC DVCDYTSTTY VGVRNHRRIH NSDKPYRCSL CGYVCSHPPS LKSHMWKHAS DQNYNYEQVN KAINDAISQS GRVLGKSPGK TQLKSSEESA DPVTGSSENA VSSSELMSQT PSEVLGTNEN EKLSPTSNTS YSLEKISSLA PPSMEYCVLL FCCCICGFES TSKENLLDHM KEHEGEIVNI ILNKDHNTAL NTN
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