Solute carrier family 7 member 13 (SLC7A13)

About Solute carrier family 7 member 13

Solute carrier family 7 member 13 (SLC7A13) is a protein from Homo sapiens identified by UniProt accession Q8TCU3, 470 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Solute carrier family 7 member 13
UniProt accession	Q8TCU3
Gene	SLC7A13
Organism	Homo sapiens
Length	470 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

creatinine measurement · score 0.32
self reported educational attainment · score 0.29
cystatin C measurement · score 0.29
low density lipoprotein cholesterol measurement · score 0.28
mathematical ability · score 0.27
glomerular filtration rate · score 0.26
urate measurement · score 0.25
total cholesterol measurement · score 0.20
cognitive function measurement · score 0.20
neutrophil count · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TCU3-F1	alphafold	PREDICTED	88.19	—

Amino-acid sequence (470 residues)

MDRGEKIQLK RVFGYWWGTS FLLINIIGAG IFVSPKGVLA YSCMNVGVSL CVWAGCAILA MTSTLCSAEI SISFPCSGAQ YYFLKRYFGS TVAFLNLWTS LFLGSGVVAG QALLLAEYSI QPFFPSCSVP KLPKKCLALA MLWIVGILTS RGVKEVTWLQ IASSVLKVSI LSFISLTGVV FLIRGKKENV ERFQNAFDAE LPDISHLIQA IFQGYFAYSG GACFTLIAGE LKKPRTTIPK CIFTALPLVT VVYLLVNISY LTVLTPREIL SSDAVAITWA DRAFPSLAWI MPFAISTSLF SNLLISIFKS SRPIYLASQE GQLPLLFNTL NSHSSPFTAV LLLVTLGSLA IILTSLIDLI NYIFFTGSLW SILLMIGILR RRYQEPNLSI PYKVFLSFPL ATIVIDVGLV VIPLVKSPNV HYVYVLLLVL SGLLFYIPLI HFKIRLAWFE KMTCYLQLLF NICLPDVSEE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards