About WAP four-disulfide core domain protein 5
WAP four-disulfide core domain protein 5 (WFDC5) is a protein
from Homo sapiens identified by UniProt accession
Q8TCV5, 224 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | WAP four-disulfide core domain protein 5 |
|---|
| UniProt accession | Q8TCV5 |
|---|
| Gene | WFDC5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- eye colour measurement · score 0.18
- blood protein measurement · score 0.12
- bipolar disorder · score 0.07
- mean platelet volume · score 0.04
- dysplasia · score 0.01
- esophageal squamous cell carcinoma · score 0.00
- lung adenocarcinoma · score 0.00
- neoplasm · score 0.00
- cutaneous lupus erythematosus · score 0.00
- melanoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCV5-F1 | alphafold | PREDICTED | 68.18 | — |
Amino-acid sequence (224 residues)
MRTQSLLLLG ALLAVGSQLP AVFGRKKGEK SGGCPPDDGP CLLSVPDQCV EDSQCPLTRK CCYRACFRQC VPRVSVKLGS CPEDQLRCLS PMNHLCHKDS DCSGKKRCCH SACGRDCRDP ARGTAPGCPG QANSDLGSVA LHLSWGPTER VHDGRPGALP AGQHYLYQRW FQPSDNHWPA DTSLQPIHPW FLLLGVKVHS LSSEEGLCIT PVLCTTAIRA SHPS
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