About CD99 antigen-like protein 2
CD99 antigen-like protein 2 (CD99L2) is a protein
from Homo sapiens identified by UniProt accession
Q8TCZ2, 262 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | CD99 antigen-like protein 2 |
|---|
| UniProt accession | Q8TCZ2 |
|---|
| Gene | CD99L2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 262 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.18
- head and neck squamous cell carcinoma · score 0.11
- response to vaccine · score 0.02
- cytokine measurement · score 0.02
- neoplasm · score 0.02
- Ewing sarcoma · score 0.01
- Sepsis · score 0.01
- Alzheimer disease · score 0.01
- Neurodevelopmental disorder · score 0.01
- infect · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TCZ2-F1 | alphafold | PREDICTED | 56.07 | — |
Amino-acid sequence (262 residues)
MVAWRSAFLV CLAFSLATLV QRGSGDFDDF NLEDAVKETS SVKQPWDHTT TTTTNRPGTT RAPAKPPGSG LDLADALDDQ DDGRRKPGIG GRERWNHVTT TTKRPVTTRA PANTLGNDFD LADALDDRND RDDGRRKPIA GGGGFSDKDL EDIVGGGEYK PDKGKGDGRY GSNDDPGSGM VAEPGTIAGV ASALAMALIG AVSSYISYQQ KKFCFSIQQG LNADYVKGEN LEAVVCEEPQ VKYSTLHTQS AEPPPPPEPA RI
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