About Retinoic acid early transcript 1E
Retinoic acid early transcript 1E (RAET1E) is a protein
from Homo sapiens identified by UniProt accession
Q8TD07, 263 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Retinoic acid early transcript 1E |
|---|
| UniProt accession | Q8TD07 |
|---|
| Gene | RAET1E |
|---|
| Organism | Homo sapiens |
|---|
| Length | 263 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.32
- myeloid sarcoma · score 0.07
- refractive error measurement · score 0.07
- neoplasm · score 0.05
- esophageal adenocarcinoma · score 0.03
- atherosclerosis · score 0.02
- coronary artery disease · score 0.02
- cancer · score 0.02
- hepatocellular carcinoma · score 0.01
- acute myeloid leukemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TD07-F1 | alphafold | PREDICTED | 81.60 | — |
Amino-acid sequence (263 residues)
MRRISLTSSP VRLLLFLLLL LIALEIMVGG HSLCFNFTIK SLSRPGQPWC EAQVFLNKNL FLQYNSDNNM VKPLGLLGKK VYATSTWGEL TQTLGEVGRD LRMLLCDIKP QIKTSDPSTL QVEMFCQREA ERCTGASWQF ATNGEKSLLF DAMNMTWTVI NHEASKIKET WKKDRGLEKY FRKLSKGDCD HWLREFLGHW EAMPEPTVSP VNASDIHWSS SSLPDRWIIL GAFILLVLMG IVLICVWWQN GEWQAGLWPL RTS
Explore Retinoic acid early transcript 1E with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets