Zinc finger protein 675 (ZNF675)

About Zinc finger protein 675

Zinc finger protein 675 (ZNF675) is a protein from Homo sapiens identified by UniProt accession Q8TD23, 568 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Zinc finger protein 675
UniProt accession	Q8TD23
Gene	ZNF675
Organism	Homo sapiens
Length	568 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

cortical surface area measurement · score 0.41
brain measurement · score 0.32
Testicular Germ Cell Tumor · score 0.28
blood protein measurement · score 0.22
upper extremity fracture · score 0.07
glioblastoma multiforme · score 0.03
osteosarcoma · score 0.02
psoriasis · score 0.02
infection · score 0.02
infect · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TD23-F1	alphafold	PREDICTED	71.98	—

Amino-acid sequence (568 residues)

MGLLTFRDVA IEFSLEEWQC LDTAQRNLYK NVILENYRNL VFLGIAVSKQ DLITCLEQEK EPLTVKRHEM VNEPPVMCSH FAQEFWPEQN IKDSFEKVTL RRYEKCGNDN FQLKGCKSVD ECKLHKGGYN GLNQCLPTMQ SKMFQCDKYV KVFNKFSHSD RHKIKHMENK PFKCKECGRS FCMLSHLTRH ERNYTKVNFC KCEECEKAVN QSSKLTKHKR IYTCEKLYKC QECDRTFNQF SNLTEYKKDY AREKPYKCEE CGKAFNQSSH LTTHKIIHTG EKPYKCEECG KAFNQFSNLT THKKIHTGEQ PYICEECGKA FTQSSTLTTH KRIHTGEKPY KCEECGKAFN RSSKLTEHKN IHTGEQPYKC EECGKAFNRS SNLTEHRKIH TEEKPYKCKE CGKAFKHSSA LTTHKRIHTG EKPYKCEECG KAFNRSSKLT EHKKLHTGKK PYKCEECGKA FIQSSKLTEH KKIHSGEIPY KCEECGKAFK HSSSLTTHKR IHTGEKPYKC EECGKAFSRS SKLTEHKIIH TGEKPYKCER CDKAFNQSAN LTKHKKIHTG EKLQNWNV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards