Small ribosomal subunit protein eS4, Y isoform 2…

About Small ribosomal subunit protein eS4, Y isoform 2

Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) is a protein from Homo sapiens identified by UniProt accession Q8TD47, 263 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS4, Y isoform 2
UniProt accession	Q8TD47
Gene	RPS4Y2
Organism	Homo sapiens
Length	263 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Azoospermia · score 0.01
azoospermia · score 0.01
Infertility · score 0.00
myeloid leukemia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TD47-F1	alphafold	PREDICTED	95.47	—

Amino-acid sequence (263 residues)

MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIVFLRN RLKYALTGDE VKKICMQHFL KIDGKVRVDI TYPAGFIDVI SIEKTGEHFR LVYNTKGCFA VHRITVEEAK YKLCKVRKIT VGTKGIPHLV THDARTIRYP DPLIKVNDTV QIDLGTGKIT SFIKFDTGNV CMVIAGANLG RVGVITNRER HPGSCDVVHV KDANGNSFAT RISNIFVIGN GNKPWISLPR GKGIRLTIAE ERDKRLAAKQ SSG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2)