About Myozenin-3
Myozenin-3 (MYOZ3) is a protein
from Homo sapiens identified by UniProt accession
Q8TDC0, 251 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Myozenin-3 |
| UniProt accession | Q8TDC0 |
| Gene | MYOZ3 |
| Organism | Homo sapiens |
| Length | 251 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- hematocrit · score 0.10
- red blood cell density measurement · score 0.06
- erythrocyte count · score 0.06
- lumbar disc degeneration · score 0.06
- hemoglobin measurement · score 0.05
- leukocyte count · score 0.03
- acute quadriplegic myopathy · score 0.01
- autism · score 0.01
- endometrial carcinoma · score 0.00
- myofibrillar myopathy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8TDC0-F1 | alphafold | PREDICTED | 60.53 | — |
Amino-acid sequence (251 residues)
MIPKEQKGPV MAAMGDLTEP VPTLDLGKKL SVPQDLMMEE LSLRNNRGSL LFQKRQRRVQ KFTFELAASQ RAMLAGSARR KVTGTAESGT VANANGPEGP NYRSELHIFP ASPGASLGGP EGAHPAAAPA GCVPSPSALA PGYAEPLKGV PPEKFNHTAI SKGYRCPWQE FVSYRDYQSD GRSHTPSPND YRNFNKTPVP FGGPLVGGTF PRPGTPFIPE PLSGLELLRL RPSFNRVAQG WVRNLPESEE L
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