About Breast carcinoma-amplified sequence 4
Breast carcinoma-amplified sequence 4 (BCAS4) is a protein
from Homo sapiens identified by UniProt accession
Q8TDM0, 211 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Breast carcinoma-amplified sequence 4 |
|---|
| UniProt accession | Q8TDM0 |
|---|
| Gene | BCAS4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 211 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- non-melanoma skin carcinoma · score 0.28
- skin cancer · score 0.25
- basal cell carcinoma · score 0.24
- skin neoplasm · score 0.21
- skin carcinoma · score 0.19
- keratinocyte carcinoma · score 0.17
- sex hormone-binding globulin measurement · score 0.08
- prostate carcinoma · score 0.07
- age at menopause · score 0.07
- gut microbiome measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TDM0-F1 | alphafold | PREDICTED | 71.48 | — |
Amino-acid sequence (211 residues)
MQRTGGGAPR PGRNHGLPGS LRQPDPVALL MLLVDADQPE PMRSGARELA LFLTPEPGAE AKEVEETIEG MLLRLEEFCS LADLIRSDTS QILEENIPVL KAKLTEMRGI YAKVDRLEAF VKMVGHHVAF LEADVLQAER DHGAFPQALR RWLGSAGLPS FRNVECSGTI PARCNLRLPG SSDSPASASQ VAGITEVTCT GARDVRAAHT V
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