About Oxoeicosanoid receptor 1
Oxoeicosanoid receptor 1 (OXER1) is a protein
from Homo sapiens identified by UniProt accession
Q8TDS5, 384 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Oxoeicosanoid receptor 1 |
|---|
| UniProt accession | Q8TDS5 |
|---|
| Gene | OXER1 |
|---|
| Organism | Homo sapiens |
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| Length | 384 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (2)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (74)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.26
- platelet count · score 0.24
- systolic blood pressure · score 0.23
- diastolic blood pressure · score 0.23
- hypertension · score 0.23
- mean corpuscular volume · score 0.23
- smoking status measurement · score 0.22
- white matter hyperintensity measurement · score 0.21
- refractive error measurement · score 0.20
- mean corpuscular hemoglobin · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TDS5-F1 | alphafold | PREDICTED | 81.66 | — |
Amino-acid sequence (384 residues)
MELHNLSSPS PSLSSSVLPP SFSPSPSSAP SAFTTVGGSS GGPCHPTSSS LVSAFLAPIL ALEFVLGLVG NSLALFIFCI HTRPWTSNTV FLVSLVAADF LLISNLPLRV DYYLLHETWR FGAAACKVNL FMLSTNRTAS VVFLTAIALN RYLKVVQPHH VLSRASVGAA ARVAGGLWVG ILLLNGHLLL STFSGPSCLS YRVGTKPSAS LRWHQALYLL EFFLPLALIL FAIVSIGLTI RNRGLGGQAG PQRAMRVLAM VVAVYTICFL PSIIFGMASM VAFWLSACRS LDLCTQLFHG SLAFTYLNSV LDPVLYCFSS PNFLHQSRAL LGLTRGRQGP VSDESSYQPS RQWRYREASR KAEAIGKLKV QGEVSLEKEG SSQG
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