Mas-related G-protein coupled receptor member D (MRGPRD)

About Mas-related G-protein coupled receptor member D

Mas-related G-protein coupled receptor member D (MRGPRD) is a protein from Homo sapiens identified by UniProt accession Q8TDS7, 321 residues long. MolForge cross-references it against 0 known binders and 268 disease associations.

Target properties

Protein name	Mas-related G-protein coupled receptor member D
UniProt accession	Q8TDS7
Gene	MRGPRD
Organism	Homo sapiens
Length	321 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TDS7-F1	alphafold	PREDICTED	85.43	—

Amino-acid sequence (321 residues)

MNQTLNSSGT VESALNYSRG STVHTAYLVL SSLAMFTCLC GMAGNSMVIW LLGFRMHRNP FCIYILNLAA ADLLFLFSMA STLSLETQPL VNTTDKVHEL MKRLMYFAYT VGLSLLTAIS TQRCLSVLFP IWFKCHRPRH LSAWVCGLLW TLCLLMNGLT SSFCSKFLKF NEDRCFRVDM VQAALIMGVL TPVMTLSSLT LFVWVRRSSQ QWRRQPTRLF VVVLASVLVF LICSLPLSIY WFVLYWLSLP PEMQVLCFSL SRLSSSVSSS ANPVIYFLVG SRRSHRLPTR SLGTVLQQAL REEPELEGGE TPTVGTNEMG A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards