About Elongator complex protein 5
Elongator complex protein 5 (ELP5) is a protein
from Homo sapiens identified by UniProt accession
Q8TE02, 300 residues long.
MolForge cross-references it against 0 known binders and
46 disease associations.
Target properties
| Protein name | Elongator complex protein 5 |
|---|
| UniProt accession | Q8TE02 |
|---|
| Gene | ELP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 300 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (46)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- birth weight · score 0.24
- breast adenocarcinoma · score 0.22
- vital capacity · score 0.14
- body height at birth · score 0.13
- systolic blood pressure · score 0.13
- diastolic blood pressure · score 0.12
- alkaline phosphatase measurement · score 0.12
- hearing loss · score 0.12
- eosinophil count · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TE02-F1 | alphafold | PREDICTED | 78.94 | — |
Amino-acid sequence (300 residues)
MLDSLLALGG LVLLRDSVEW EGRSLLKALV KKSALCGEQV HILGCEVSEE EFREGFDSDI NNRLVYHDFF RDPLNWSKTE EAFPGGPLGA LRAMCKRTDP VPVTIALDSL SWLLLRLPCT TLCQVLHAVS HQDSCPGDSS SVGKVSVLGL LHEELHGPGP VGALSSLAQT EVTLGGTMGQ ASAHILCRRP RQRPTDQTQW FSILPDFSLD LQEGPSVESQ PYSDPHIPPV DPTTHLTFNL HLSKKEREAR DSLILPFQFS SEKQQALLRP RPGQATSHIF YEPDAYDDLD QEDPDDDLDI
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