About U3 small nucleolar RNA-associated protein 15 homolog
U3 small nucleolar RNA-associated protein 15 homolog (UTP15) is a protein
from Homo sapiens identified by UniProt accession
Q8TED0, 518 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | U3 small nucleolar RNA-associated protein 15 homolog |
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| UniProt accession | Q8TED0 |
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| Gene | UTP15 |
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| Organism | Homo sapiens |
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| Length | 518 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- protein measurement · score 0.32
- multiple sclerosis · score 0.25
- Alzheimer disease · score 0.25
- lysosomal storage disease · score 0.25
- Parkinson disease · score 0.25
- lymphocyte count · score 0.19
- mean platelet volume · score 0.13
- endometrial cancer · score 0.10
- sensorineural hearing loss · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TED0-F1 | alphafold | PREDICTED | 82.40 | — |
Amino-acid sequence (518 residues)
MAGYKPVAIQ TYPILGEKIT QDTLYWNNYK TPVQIKEFGA VSKVDFSPQP PYNYAVTASS RIHIYGRYSQ EPIKTFSRFK DTAYCATFRQ DGRLLVAGSE DGGVQLFDIS GRAPLRQFEG HTKAVHTVDF TADKYHVVSG ADDYTVKLWD IPNSKEILTF KEHSDYVRCG CASKLNPDLF ITGSYDHTVK MFDARTSESV LSVEHGQPVE SVLLFPSGGL LVSAGGRYVK VWDMLKGGQL LVSLKNHHKT VTCLCLSSSG QRLLSGSLDR KVKVYSTTSY KVVHSFDYAA SILSLALAHE DETIVVGMTN GILSVKHRKS EAKKESLPRR RRPAYRTFIK GKNYMKQRDD ILINRPAKKH LELYDRDLKH FRISKALDRV LDPTCTIKTP EITVSIIKEL NRRGVLANAL AGRDEKEISH VLNFLIRNLS QPRFAPVLIN AAEIIIDIYL PVIGQSPVVD KKFLLLQGLV EKEIDYQREL LETLGMMDML FATMRRKEGT SVLEHTSDGF PENKKIES
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