Probable glutathione peroxidase 8 (GPX8)

About Probable glutathione peroxidase 8

Probable glutathione peroxidase 8 (GPX8) is a protein from Homo sapiens identified by UniProt accession Q8TED1, 209 residues long. MolForge cross-references it against 0 known binders and 147 disease associations.

Target properties

Protein name	Probable glutathione peroxidase 8
UniProt accession	Q8TED1
Gene	GPX8
Organism	Homo sapiens
Length	209 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TED1-F1	alphafold	PREDICTED	93.07	—

Amino-acid sequence (209 residues)

MEPLAAYPLK CSGPRAKVFA VLLSIVLCTV TLFLLQLKFL KPKINSFYAF EVKDAKGRTV SLEKYKGKVS LVVNVASDCQ LTDRNYLGLK ELHKEFGPSH FSVLAFPCNQ FGESEPRPSK EVESFARKNY GVTFPIFHKI KILGSEGEPA FRFLVDSSKK EPRWNFWKYL VNPEGQVVKF WKPEEPIEVI RPDIAALVRQ VIIKKKEDL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards