About Histone deacetylase complex subunit SAP25
Histone deacetylase complex subunit SAP25 (SAP25) is a protein
from Homo sapiens identified by UniProt accession
Q8TEE9, 199 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Histone deacetylase complex subunit SAP25 |
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| UniProt accession | Q8TEE9 |
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| Gene | SAP25 |
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| Organism | Homo sapiens |
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| Length | 199 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (12)
Diseases linked to this target (Open Targets).
- brain volume measurement · score 0.10
- neuroimaging measurement · score 0.10
- mean corpuscular volume · score 0.09
- reticulocyte count · score 0.08
- high density lipoprotein cholesterol measurement · score 0.05
- reticulocyte measurement · score 0.05
- mean reticulocyte volume · score 0.04
- mean platelet volume · score 0.03
- bowel opening frequency · score 0.03
- mean corpuscular hemoglobin concentration · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TEE9-F1 | alphafold | PREDICTED | 56.91 | — |
Amino-acid sequence (199 residues)
MTPLAPWDPK YEAKAGPRPV WGANCSSGAS FSGRTLCHPS FWPLYEAASG RGLRPVAPAT GHWNGQQAPP DAGFPVVCCE DVFLSDPLLP RGQRVPLYLS KAPQQMMGSL KLLPPPPIMS ARVLPRPSPS RGPSTAWLSG PELIALTGLL QMSQGEPRPS SSAVGPPDHT SDPPSPCGSP SSSQGADLSL PQTPDTHCP
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