Uncharacterized protein C10orf105 (C10orf105)

About Uncharacterized protein C10orf105

Uncharacterized protein C10orf105 (C10orf105) is a protein from Homo sapiens identified by UniProt accession Q8TEF2, 133 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	Uncharacterized protein C10orf105
UniProt accession	Q8TEF2
Gene	C10orf105
Organism	Homo sapiens
Length	133 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

Pituitary Gland Adenoma · score 0.54
Usher syndrome type 1 · score 0.53
Usher syndrome · score 0.53
deafness · score 0.51
hearing loss, autosomal recessive · score 0.51
Rare genetic deafness · score 0.46
genetic disorder · score 0.41
Retinal dystrophy · score 0.35
ear malformation · score 0.27
Abnormality of the ear · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TEF2-F1	alphafold	PREDICTED	63.37	—

Amino-acid sequence (133 residues)

MSTEGPSLAS SPAISPLAFL SAPVTPGTLA EATDPLPMLI ALACIFLLLA TCLLFMTLCK PAALDPSRRR AHECMPHHPG SPSEPQLRLW KRLGSLRLSL HSFRHGRPTV PRQPLPGPED NRSHCDYMES TKM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards