Nuclear pore membrane glycoprotein 210 (NUP210)

About Nuclear pore membrane glycoprotein 210

Nuclear pore membrane glycoprotein 210 (NUP210) is a protein from Homo sapiens identified by UniProt accession Q8TEM1, 1887 residues long. MolForge cross-references it against 0 known binders and 192 disease associations.

Target properties

Protein name	Nuclear pore membrane glycoprotein 210
UniProt accession	Q8TEM1
Gene	NUP210
Organism	Homo sapiens
Length	1887 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (192)

Diseases linked to this target (Open Targets).

influenza · score 0.54
HIV infection · score 0.54
viral disease · score 0.53
COVID-19 · score 0.37
Histiocytosis · score 0.37
platelet count · score 0.35
mathematical ability · score 0.33
serum alanine aminotransferase measurement · score 0.32
mean platelet volume · score 0.29
clear cell renal carcinoma · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TEM1-F1	alphafold	PREDICTED	79.59	—

Amino-acid sequence (1887 residues)

MAARGRGLLL LTLSVLLAAG PSAAAAKLNI PKVLLPFTRA TRVNFTLEAS EGCYRWLSTR PEVASIEPLG LDEQQCSQKA VVQARLTQPA RLTSIIFAED ITTGQVLRCD AIVDLIHDIQ IVSTTRELYL EDSPLELKIQ ALDSEGNTFS TLAGLVFEWT IVKDSEADRF SDSHNALRIL TFLESTYIPP SYISEMEKAA KQGDTILVSG MKTGSSKLKA RIQEAVYKNV RPAEVRLLIL ENILLNPAYD VYLMVGTSIH YKVQKIRQGK ITELSMPSDQ YELQLQNSIP GPEGDPARPV AVLAQDTSMV TALQLGQSSL VLGHRSIRMQ GASRLPNSTI YVVEPGYLGF TVHPGDRWVL ETGRLYEITI EVFDKFSNKV YVSDNIRIET VLPAEFFEVL SSSQNGSYHR IRALKRGQTA IDAALTSVVD QDGGVHILQV PVWNQQEVEI HIPITLYPSI LTFPWQPKTG AYQYTIRAHG GSGNFSWSSS SHLVATVTVK GVMTTGSDIG FSVIQAHDVQ NPLHFGEMKV YVIEPHSMEF APCQVEARVG QALELPLRIS GLMPGGASEV VTLSDCSHFD LAVEVENQGV FQPLPGRLPP GSEHCSGIRV KAEAQGSTTL LVSYRHGHVH LSAKITIAAY LPLKAVDPSS VALVTLGSSK EMLFEGGPRP WILEPSKFFQ NVTAEDTDSI GLALFAPHSS RNYQQHWILV TCQALGEQVI ALSVGNKPSL TNPFPAVEPA VVKFVCAPPS RLTLAPVYTS PQLDMSCPLL QQNKQVVPVS SHRNPRLDLA AYDQEGRRFD NFSSLSIQWE STRPVLASIE PELPMQLVSQ DDESGQKKLH GLQAILVHEA SGTTAITATA TGYQESHLSS ARTKQPHDPL VPLSASIELI LVEDVRVSPE EVTIYNHPGI QAELRIREGS GYFFLNTSTA DVVKVAYQEA RGVAMVHPLL PGSSTIMIHD LCLVFPAPAK AVVYVSDIQE LYIRVVDKVE IGKTVKAYVR VLDLHKKPFL AKYFPFMDLK LRAASPIITL VALDEALDNY TITFLIRGVA IGQTSLTASV TNKAGQRINS APQQIEVFPP FRLMPRKVTL LIGATMQVTS EGGPQPQSNI LFSISNESVA LVSAAGLVQG LAIGNGTVSG LVQAVDAETG KVVIISQDLV QVEVLLLRAV RIRAPIMRMR TGTQMPIYVT GITNHQNPFS FGNAVPGLTF HWSVTKRDVL DLRGRHHEAS IRLPSQYNFA MNVLGRVKGR TGLRVVVKAV DPTSGQLYGL ARELSDEIQV QVFEKLQLLN PEIEAEQILM SPNSYIKLQT NRDGAASLSY RVLDGPEKVP VVHVDEKGFL ASGSMIGTST IEVIAQEPFG ANQTIIVAVK VSPVSYLRVS MSPVLHTQNK EALVAVPLGM TVTFTVHFHD NSGDVFHAHS SVLNFATNRD DFVQIGKGPT NNTCVVRTVS VGLTLLRVWD AEHPGLSDFM PLPVLQAISP ELSGAMVVGD VLCLATVLTS LEGLSGTWSS SANSILHIDP KTGVAVARAV GSVTVYYEVA GHLRTYKEVV VSVPQRIMAR HLHPIQTSFQ EATASKVIVA VGDRSSNLRG ECTPTQREVI QALHPETLIS CQSQFKPAVF DFPSQDVFTV EPQFDTALGQ YFCSITMHRL TDKQRKHLSM KKTALVVSAS LSSSHFSTEQ VGAEVPFSPG LFADQAEILL SNHYTSSEIR VFGAPEVLEN LEVKSGSPAV LAFAKEKSFG WPSFITYTVG VLDPAAGSQG PLSTTLTFSS PVTNQAIAIP VTVAFVVDRR GPGPYGASLF QHFLDSYQVM FFTLFALLAG TAVMIIAYHT VCTPRDLAVP AALTPRASPG HSPHYFAASS PTSPNALPPA RKASPPSGLW SPAYASH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards