Cytochrome c oxidase subunit 7B2, mitochondrial…

About Cytochrome c oxidase subunit 7B2, mitochondrial

Cytochrome c oxidase subunit 7B2, mitochondrial (COX7B2) is a protein from Homo sapiens identified by UniProt accession Q8TF08, 81 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.

Target properties

Protein name	Cytochrome c oxidase subunit 7B2, mitochondrial
UniProt accession	Q8TF08
Gene	COX7B2
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (107)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.21
alcohol consumption measurement · score 0.20
alcohol use disorder measurement · score 0.20
azoospermia · score 0.11
male infertility with teratozoospermia due to single gene mutation · score 0.09
systolic blood pressure · score 0.08
spermatogenic failure 72 · score 0.07
partial chromosome Y deletion · score 0.07
spermatogenic failure 46 · score 0.07
spermatogenic failure 18 · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TF08-F1	alphafold	PREDICTED	90.06	—

Amino-acid sequence (81 residues)

MMFPLARNAL SSLKIQSILQ SMARHSHVKH SPDFHDKYGN AVLASGTAFC VATWVFTATQ IGIEWNLSPV GRVTPKEWKH Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Cytochrome c oxidase subunit 7B2, mitochondrial (COX7B2)