About Zinc finger protein 721
Zinc finger protein 721 (ZNF721) is a protein
from Homo sapiens identified by UniProt accession
Q8TF20, 911 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Zinc finger protein 721 |
|---|
| UniProt accession | Q8TF20 |
|---|
| Gene | ZNF721 |
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| Organism | Homo sapiens |
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| Length | 911 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.23
- nasopharyngeal neoplasm · score 0.18
- Thymoma · score 0.01
- Ataxia-telangiectasia · score 0.01
- cancer · score 0.00
- squamous cell carcinoma · score 0.00
- gastric carcinoma · score 0.00
- heroin dependence · score 0.00
- type 1 diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TF20-F1 | alphafold | PREDICTED | 71.34 | — |
Amino-acid sequence (911 residues)
MCSHFTQDFL PVQGIEDSFH KLILRRYEKC GHDNLQLRKG CKSMNVCKVQ KGVYNGINKC LSNTQSKIFQ CNARVKVFSK FANSNKDKTR HTGEKHFKCN ECGKSFQKFS DLTQHKGIHA GEKPYTCEER GKDFGWYTDL NQHKKIHTGE KPYKCEECGK AFNRSTNLTA HKRIHNREKA YTGEDRDRAF GWSTNLNEYK KIHTGDKPYK CKECGKAFMH SSHLNKHEKI HTGEKPYKCK ECGKVISSSS SFAKHKRIHT GEKPFKCLEC GKAFNISTTL TKHRRIHTGE KPYTCEVCGK AFRQSANLYV HRRIHTGEKP YTCGECGKTF RQSANLYVHR RIHTGEKPYK CEDCGKAFGR YTALNQHKKI HTGEKPYKCE ECGKAFNSST NLTAHKRIHT REKPYTCEDR GRAFGLSTNL NEYKKIHTGD KPYKCKECGK AFIHSLHLNK HEKIHTGKKP YKCKQCGKVI TSSSSFAKHK RIHTGEKPFE CLECGKAFTS STTLTKHRRI HTGEKPYTCE VCGKAFRQSA ILYVHRRIHT GEKPYTCEEC GKTFRQSANL YVHRRIHTGE KPYKCEECGK AFGRYTDLNQ HKKIHTGEKL YKCEECGKDF VWYTDLNQQK KIYTGEKPYK CEECGKAFAP STDLNQHTKI LTGEQSYKCE ECGKAFGWSI ALNQHKKIHT GEKPYKCEEC GKAFSRSRNL TTHRRVHTRE KPYKCEDRGR SFGWSTNLNE YKKIHTGDKL YKCKECGKVF KQSSHLNRHE KIHTGKKPYK CKECGKVITS SSSFAKHKRI HTGEKPFKCL ECGKAFTSST TLTKHRRIHT GEKPYTCEEC GKAFRQSAIL YVHRRIHTGE KPYTCGECGK TFRQSANLYA HKKIHTGEKP YTCGDCGKTF RQSANLYAHK KIHTGDKTIQ V
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