About C2 calcium-dependent domain-containing protein 4C
C2 calcium-dependent domain-containing protein 4C (C2CD4C) is a protein
from Homo sapiens identified by UniProt accession
Q8TF44, 421 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | C2 calcium-dependent domain-containing protein 4C |
| UniProt accession | Q8TF44 |
| Gene | C2CD4C |
| Organism | Homo sapiens |
| Length | 421 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- bulimia nervosa · score 0.05
- lymphocyte count · score 0.04
- Renal glucosuria · score 0.03
- lymphocyte percentage of leukocytes · score 0.02
- Tetralogy of Fallot · score 0.01
- breast carcinoma · score 0.00
- Fibroadenoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8TF44-F1 | alphafold | PREDICTED | 64.90 | — |
Amino-acid sequence (421 residues)
MRKTNMWFLE RLRGSGENGA ARGVGSEAGD KASKGPLYSN VLTPDKIPDF FIPPKLPSGP AEGEGQAALG PSTSEQNLAS AAPRQTPRSP RLPAKLAAES KSLLKAATRH VIQIESAEDW LSEEATDADP QAQGAMSLPS VPKAQTSYGF AMLAESPHTR RKESLFHSEH GALAQVGSPG AGRRRAAAKA NGGDGGPREA GGALMSPGRY FSGGESDTGS SAESSPFGSP LLSRSVSLLK GFAQDSQAKV SQLRHSVGRH GSLSADDSTP DASPGSRRRL TRRAPPEPGP ESGQARGEHT VHVGPRGSVR LLAEYEAGQA RLRVHLLAAE GLYDRLCDAR SINCCVGLCL VPGKLQKQRS TIVKNSRRPV FNEDFFFDGL GPASVRKLAL RIKVVNKGSS LKRDTLLGEK ELPLTSLLPF L
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