C2 calcium-dependent domain-containing protein 4C (C2CD4C)

Homo sapiens — UniProt Q8TF44

Gene: C2CD4CHomo sapiensSwissProt reviewed

About C2 calcium-dependent domain-containing protein 4C

C2 calcium-dependent domain-containing protein 4C (C2CD4C) is a protein from Homo sapiens identified by UniProt accession Q8TF44, 421 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein nameC2 calcium-dependent domain-containing protein 4C
UniProt accessionQ8TF44
GeneC2CD4C
OrganismHomo sapiens
Length421 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (7)

Diseases linked to this target (Open Targets).

  • bulimia nervosa · score 0.05
  • lymphocyte count · score 0.04
  • Renal glucosuria · score 0.03
  • lymphocyte percentage of leukocytes · score 0.02
  • Tetralogy of Fallot · score 0.01
  • breast carcinoma · score 0.00
  • Fibroadenoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8TF44-F1alphafoldPREDICTED64.90—

Amino-acid sequence (421 residues)

MRKTNMWFLE RLRGSGENGA ARGVGSEAGD KASKGPLYSN VLTPDKIPDF FIPPKLPSGP AEGEGQAALG PSTSEQNLAS AAPRQTPRSP RLPAKLAAES KSLLKAATRH VIQIESAEDW LSEEATDADP QAQGAMSLPS VPKAQTSYGF AMLAESPHTR RKESLFHSEH GALAQVGSPG AGRRRAAAKA NGGDGGPREA GGALMSPGRY FSGGESDTGS SAESSPFGSP LLSRSVSLLK GFAQDSQAKV SQLRHSVGRH GSLSADDSTP DASPGSRRRL TRRAPPEPGP ESGQARGEHT VHVGPRGSVR LLAEYEAGQA RLRVHLLAAE GLYDRLCDAR SINCCVGLCL VPGKLQKQRS TIVKNSRRPV FNEDFFFDGL GPASVRKLAL RIKVVNKGSS LKRDTLLGEK ELPLTSLLPF L

Explore C2 calcium-dependent domain-containing protein 4C with MolForge

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Quick facts

UniProtQ8TF44
GeneC2CD4C
OrganismHomo sapiens
Length421
Binders0
Diseases7
View on UniProt