About Leucine-rich repeat-containing protein 15
Leucine-rich repeat-containing protein 15 (LRRC15) is a protein
from Homo sapiens identified by UniProt accession
Q8TF66, 581 residues long.
MolForge cross-references it against 0 known binders and
116 disease associations.
Target properties
| Protein name | Leucine-rich repeat-containing protein 15 |
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| UniProt accession | Q8TF66 |
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| Gene | LRRC15 |
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| Organism | Homo sapiens |
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| Length | 581 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TF66-F1 | alphafold | PREDICTED | 83.58 | — |
Amino-acid sequence (581 residues)
MPLKHYLLLL VGCQAWGAGL AYHGCPSECT CSRASQVECT GARIVAVPTP LPWNAMSLQI LNTHITELNE SPFLNISALI ALRIEKNELS RITPGAFRNL GSLRYLSLAN NKLQVLPIGL FQGLDSLESL LLSSNQLLQI QPAHFSQCSN LKELQLHGNH LEYIPDGAFD HLVGLTKLNL GKNSLTHISP RVFQHLGNLQ VLRLYENRLT DIPMGTFDGL VNLQELALQQ NQIGLLSPGL FHNNHNLQRL YLSNNHISQL PPSVFMQLPQ LNRLTLFGNS LKELSPGIFG PMPNLRELWL YDNHISSLPD NVFSNLRQLQ VLILSRNQIS FISPGAFNGL TELRELSLHT NALQDLDGNV FRMLANLQNI SLQNNRLRQL PGNIFANVNG LMAIQLQNNQ LENLPLGIFD HLGKLCELRL YDNPWRCDSD ILPLRNWLLL NQPRLGTDTV PVCFSPANVR GQSLIIINVN VAVPSVHVPE VPSYPETPWY PDTPSYPDTT SVSSTTELTS PVEDYTDLTT IQVTDDRSVW GMTQAQSGLA IAAIVIGIVA LACSLAACVG CCCCKKRSQA VLMQMKAPNE C
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