About Monocarboxylate transporter 10
Monocarboxylate transporter 10 (SLC16A10) is a protein
from Homo sapiens identified by UniProt accession
Q8TF71, 515 residues long.
MolForge cross-references it against 0 known binders and
177 disease associations.
Target properties
| Protein name | Monocarboxylate transporter 10 |
|---|
| UniProt accession | Q8TF71 |
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| Gene | SLC16A10 |
|---|
| Organism | Homo sapiens |
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| Length | 515 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (177)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.48
- mean corpuscular hemoglobin · score 0.46
- blood metabolite measurement · score 0.44
- mean corpuscular hemoglobin concentration · score 0.44
- erythrocyte count · score 0.43
- urate measurement · score 0.43
- red blood cell density measurement · score 0.39
- mean reticulocyte volume · score 0.39
- Red cell distribution width · score 0.38
- neurodegenerative disease · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TF71-F1 | alphafold | PREDICTED | 81.87 | — |
Amino-acid sequence (515 residues)
MVLSQEEPDS ARGTSEAQPL GPAPTGAAPP PGPGPSDSPE AAVEKVEVEL AGPATAEPHE PPEPPEGGWG WLVMLAAMWC NGSVFGIQNA CGVLFVSMLE TFGSKDDDKM VFKTAWVGSL SMGMIFFCCP IVSVFTDLFG CRKTAVVGAA VGFVGLMSSS FVSSIEPLYL TYGIIFACGC SFAYQPSLVI LGHYFKKRLG LVNGIVTAGS SVFTILLPLL LRVLIDSVGL FYTLRVLCIF MFVLFLAGFT YRPLATSTKD KESGGSGSSL FSRKKFSPPK KIFNFAIFKV TAYAVWAVGI PLALFGYFVP YVHLMKHVNE RFQDEKNKEV VLMCIGVTSG VGRLLFGRIA DYVPGVKKVY LQVLSFFFIG LMSMMIPLCS IFGALIAVCL IMGLFDGCFI SIMAPIAFEL VGAQDVSQAI GFLLGFMSIP MTVGPPIAGL LRDKLGSYDV AFYLAGVPPL IGGAVLCFIP WIHSKKQREI SKTTGKEKME KMLENQNSLL SSSSGMFKKE SDSII
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