Beta-defensin 104 (DEFB104A)

About Beta-defensin 104

Beta-defensin 104 (DEFB104A) is a protein from Homo sapiens identified by UniProt accession Q8WTQ1, 72 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Beta-defensin 104
UniProt accession	Q8WTQ1
Gene	DEFB104A
Organism	Homo sapiens
Length	72 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

endometrial cancer · score 0.21
Autosomal dominant striatal neurodegeneration · score 0.04
neuroticism measurement · score 0.04
COVID-19 · score 0.03
emotional symptom measurement · score 0.03
cancer · score 0.02
viral disease · score 0.02
infect · score 0.02
infection · score 0.02
nonpapillary renal cell carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WTQ1-F1	alphafold	PREDICTED	81.05	—

Amino-acid sequence (72 residues)

MQRLVLLLAI SLLLYQDLPV RSEFELDRIC GYGTARCRKK CRSQEYRIGR CPNTYACCLR KWDESLLNRT KP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards